The new season of All Creatures Great and Small will be welcoming some new (and famous) faces into the village of Darrowby, including Coronation Street’s Lucy-Jo Hudson and Patience’s Chris Gascoyne.
The Yorkshire Dales-set drama based on the books by real-life vet Alf Wight returns for its sixth series tonight (September 25), featuring popular character James Herriot (played by Nicholas Ralph) once again.
Since 2020, the original 1970s drama, now primarily filmed in the town of Grassington, has been rebooted by Channel 5.
But the latest instalment will be set in 1945, just as World War II comes to an end.
What is All Creatures Great and Small series 6 about?
If you’re wondering what to expect from All Creatures Great and Small series six, Channel 5 shared in its synopsis: “This time, we find our beloved Skeldale gang in a somewhat different situation as we join them in 1945, just as the war in Europe is coming to a close.
“We arrive back in Darrowby to veterinary advancements, expanded families, and new faces as they all look ahead to a brighter and more peaceful future.
It adds: "This series will see Herriot's wonderful characters navigating the opportunities that a new world brings, a host of animals great and small, and of course, each other.”
We return to Darrowby in May 1945. Tristan returns from war to find Siegfried rather chaotic and unpredictable. Shocked by his brother’s behaviour, he works with James to help ❤️
All Creatures Great and Small. Watch | Stream on 5@AllCreaturesTV @exitthelemming #allcreatures… pic.twitter.com/FWG8sb704p— Channel 5 (@channel5_tv) September 24, 2025
Who is in All Creatures Great and Small series 6? Full cast list
The returning cast of the hit Channel 5 show includes:
- Nicholas Ralph as James Herriot
- Samuel West as Siegfried Farnon
- Anna Madeley as Mrs Hall
- Rachel Shenton as Helen Herriot
- Callum Woodhouse as Tristan Farnon
- Patricia Hodge as Mrs Pumphrey
- Tony Pitts as Richard Alderson
- Imogen Clawson as Jenny
Meanwhile, the new cast members for series six are:
- Lucy-Jo Hudson (as seen in Coronation Street, Hollyoaks and Wild at Heart)
- Gaia Wise (as seen in The Dead of Winter and The Lord of the Rings: The War of the Rohirrim)
- Jonathan Hyde (as seen in The Brutalist and Titanic)
- Philip Martin Brown (as seen in Waterloo Road, Tinker Tailor Soldier Spy)
- Chris Gascoyne (as seen in The Feud and Patience)
When is All Creatures Great and Small series 6 on TV?
Series six returns tonight at 9pm (there will be six episodes aired in total).
The summary of the first episode, as shared by Radio Times, teases: “May 1945, and things look very different at Skeldale House as James is struggling with a wild and chaotic Siegfried.
“When Tristan returns from war and is shocked to see the shift in his brother, he and James decide to take action.
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“But there's also some good news around the corner for everyone.”
All remaining episodes will air weekly on Thursdays at the same time.
You can catch up on all previous series of All Creatures Great and Small via Channel 5 online.